Article
Long-Term Expansion in Platelet Lysate Increases Growth of Peripheral Blood-Derived Endothelial-Colony Forming Cells and Their Growth Factor-Induced Sprouting Capacity.
PloS one - 1 Jan 2015
Tasev Dimitar, van Wijhe Michiel H, Weijers Ester M, van Hinsbergh Victor W M, Koolwijk Pieter
Abstract excerpt
INTRODUCTION: Efficient implementation of peripheral blood-derived endothelial-colony cells (PB-ECFCs) as a therapeutical tool requires isolation and generation of a sufficient number of cells in ex vivo conditions devoid of animal-derived products. At present, little is known how the isolation and expansion procedure in xenogeneic-free conditions affects the therapeutical capacity of PB-ECFCs. RESULTS: The...
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