Article
Abolition and reversal of strain differences in behavioral responses to drugs of abuse after a brief experience.
Science (New York, N.Y.) - 21 Jul 2000
Cabib S, Orsini C, Le Moal M, Piazza P V
Abstract excerpt
Inbred strains of mice are largely used to identify the genetic basis of normal and pathological behaviors. This report demonstrates that a moderate period of food shortage, an ecologically common experience, can reverse or abolish strain differences in behavioral responses to the abused psychostimulant amphetamine. The period of food shortage occurred when the animals were mature and was terminated before the...
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