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Article

Host range and variability of calcium binding by surface loops in the capsids of canine and feline parvoviruses.

Journal of molecular biology - 14 Jul 2000

Simpson A A, Chandrasekar V, Hébert B, Sullivan G M, Rossmann M G, Parrish C R

Abstract excerpt

Canine parvovirus (CPV) emerged in 1978 as a host range variant of feline panleukopenia virus (FPV). This change of host was mediated by the mutation of five residues on the surface of the capsid. CPV and FPV enter cells by endocytosis and can be taken up by many non-permissive cell lines, showing that their host range and tissue specificity are largely determined by events occurring after cell entry. We have...

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Identifiers

PMID: 10884355
DOI: 10.1006/jmbi.2000.3868

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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