Article
Host range and variability of calcium binding by surface loops in the capsids of canine and feline parvoviruses.
Journal of molecular biology - 14 Jul 2000
Simpson A A, Chandrasekar V, Hébert B, Sullivan G M, Rossmann M G, Parrish C R
Abstract excerpt
Canine parvovirus (CPV) emerged in 1978 as a host range variant of feline panleukopenia virus (FPV). This change of host was mediated by the mutation of five residues on the surface of the capsid. CPV and FPV enter cells by endocytosis and can be taken up by many non-permissive cell lines, showin...
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