Article
The ACE I allele is associated with increased risk for ruptured intracranial aneurysms.
Journal of medical genetics - 1 Jul 2000
Keramatipour M, McConnell R S, Kirkpatrick P, Tebbs S, Furlong R A, Rubinsztein D C
Abstract excerpt
Genetic and environmental factors play roles in the aetiology of ruptured intracranial aneurysms. Hypertension has been reported as a risk factor for intracranial aneurysm haemorrhage. We have tested if genotypes at the angiotensin converting enzyme (ACE) gene locus are associated with ruptured intracranial aneurysms. The insertion/deletion polymorphism in the ACE gene was genotyped in 258 subjects presenting in...
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