Article
II genotype of the angiotensin-converting enzyme gene increases the risk for subarachnoid hemorrhage from ruptured aneurysm.
Stroke - 1 Jul 2004
Slowik Agnieszka, Borratynska Anna, Pera Joanna, Betlej Marek, Dziedzic Tomasz, Krzyszkowski Tadeusz, Czepko Ryszard, Figlewicz Denise A, Szczudlik Andrzej
Abstract excerpt
BACKGROUND AND PURPOSE: Evidence exists in support of a role of genetic factors in susceptibility to aneurysmal subarachnoid hemorrhage (SAH) in humans. Meta-analysis of 2 previous studies showed that the I allele of angiotensin-converting enzyme (ACE) gene insertion/deletion (I/D) polymorphism was a weak, but significant, risk factor for aneurysmal SAH. Moreover, a recent study has shown that the local...
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