Article
Common variants of the ACE gene and aneurysmal subarachnoid hemorrhage in a Danish population: a case-control study.
Journal of neurosurgical anesthesiology - 1 Oct 2011
Staalsø Jonatan Myrup, Nielsen Morten, Edsen Troels, Koefoed Pernille, Springborg Jacob Bertram, Moltke Finn Borgbjerg, Laursen Henning, Nielsen Henning Bay, Olsen Niels Vidiendal
Abstract excerpt
OBJECTIVE: The intron 16 insertion/deletion (I/D) polymorphism in the angiotensin-converting enzyme (ACE) gene has been associated with rupture of intracranial aneurysms, but the effect of haplotypes within ACE has not been studied. This study investigated whether ACE haplotypes including the I/D polymorphism are associated with aneurysmal subarachnoid hemorrhage. METHODS: The hypothesis was tested with a...
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