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Article

Observing conformational and activity changes of tet repressor in vivo.

Nature structural biology - 1 Jun 2000

Tiebel B, Garke K, Hillen W

Abstract excerpt

Effector triggered conformational changes of proteins such as regulators of transcription, receptors, or enzymes are the molecular basis for regulation in biology. Most proteins perform their biological functions intracellularly, in the presence of many potential interaction partners. Studies of conformational changes have mainly been performed in vitro using sophisticated physical and biochemical methods that...

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PMID: 10881195
DOI: 10.1038/75883

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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