Article
Multipoint mapping of viability and segregation distorting loci using molecular markers.
Genetics - 1 Jul 2000
Vogl C, Xu S
Abstract excerpt
In line-crossing experiments, deviations from Mendelian segregation ratios are usually observed for some markers. We hypothesize that these deviations are caused by one or more segregation-distorting loci (SDL) linked to the markers. We develop both a maximum-likelihood (ML) method and a Bayesian method to map SDL using molecular markers. The ML mapping is implemented via an EM algorithm and the Bayesian method...
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