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Article

Tests for segregation distortion in higher ploidy F1 populations.

G3 (Bethesda, Md.) - 12 Nov 2025

Gerard David, Ambrosano Guilherme Bovi, Pereira Guilherme da Silva, Garcia Antonio Augusto Franco

Abstract excerpt

F1 populations are widely used in genetic mapping studies in agriculture, where known pedigrees enable rigorous quality control measures such as segregation distortion testing. However, conventional tests for segregation distortion are inadequate for polyploids, as they fail to account for double reduction, preferential pairing, and genotype uncertainty, leading to inflated type I error rates. Prior work...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 40971889
DOI: 10.1093/g3journal/jkaf212
PMCID: PMC12611257

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