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Article

Secondary V(D)J rearrangements and B cell receptor-mediated down-regulation of recombination activating gene-2 expression in a murine B cell line.

Journal of immunology (Baltimore, Md. : 1950) - 15 Jul 2000

Maës J, Caspi Y, Rougeon F, Haimovich J, Goodhardt M

Abstract excerpt

It has recently become clear that recombination of Ig genes is not restricted to B cell precursors but that secondary rearrangements can also occur under certain conditions in phenotypically immature bone marrow and peripheral B cells. However, the nature of these cells and the regulation of secondary V(D)J recombination in response to B cell receptor (BCR) stimulation remain controversial. In the present study,...

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Source

Identifiers

PMID: 10878342
DOI: 10.4049/jimmunol.165.2.703

Genes

BCR
RAG2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Secondary V(D)J rearrangements and B cell receptor-mediated down-regulation of recombination activating gene-2 expression in a murine B cell line.PMID 10878342Read ↗

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