Article
Crystal structure of the bacterial conjugation repressor finO.
Nature structural biology - 1 Jul 2000
Ghetu A F, Gubbins M J, Frost L S, Glover J N
Abstract excerpt
The conjugative transfer of F-like plasmids is repressed by FinO, an RNA binding protein. FinO interacts with the F-plasmid encoded traJ mRNA and its antisense RNA, FinP, stabilizing FinP against endonucleolytic degradation and facilitating sense-antisense RNA recognition. Here we present the 2.0 A resolution X-ray crystal structure of FinO, lacking its flexible N-terminal extension. FinO adopts a novel,...
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