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Article

Relation between HFE mutations and mild iron-overload expression.

Molecular genetics and metabolism - 1 Apr 2000

Mura C, Le Gac G, Raguénes O, Mercier A Y, Le Guen A, Férec C

Abstract excerpt

The identification of the HFE gene involved in hemochromatosis allows genetic tests based on mutation analysis to be performed. However, discrepancies in the correlation between HFE genotypes and iron-loading status have arisen. We investigated 708 patients with various signs or symptoms suggesting a putative iron overload that, nevertheless, did not reach the current criteria for hemochromatosis diagnosis. Most...

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Source

Identifiers

PMID: 10870847
DOI: 10.1006/mgme.2000.2981

Genes

HFE

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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