Article
Microenvironment-induced cancer metastasis
1 Jan 2000
Abstract excerpt
PURPOSE: To present and evaluate clinical data suggesting that cancer metastasis may be induced by the microenvironment of the primary tumour and to discuss possible mechanisms of microenvironment-induced metastasis, based on a critical review of relevant data from studies of experimental tumours and cells in culture. CONCLUSIONS: Low oxygen tension in the primary tumour is associated with metastasis in soft...
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