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Article

Hypoxia-inducible factor-1α polymorphisms and risk of cancer metastasis: a meta-analysis.

PloS one - 1 Jan 2013

Zhang Qian, Chen Yan, Zhang Bin, Shi Bin, Weng Wenjun, Chen Zhipeng, Guo Nannan, Hua Yibing, Zhu Lingjun

Abstract excerpt

BACKGROUND: HIF-1α is a major regulator in tumor progression and metastasis which responds to hypoxia. Many studies have demonstrated that hypoxia-inducible factor1-α (HIF-1α) polymorphisms are significantly associated with cancer metastasis, but the results are inconsistent. We conducted a compr...

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Source

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Identifiers

PMID: 24015181
DOI: 10.1371/journal.pone.0070961
PMCID: PMC3756035

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24015181-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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