Article
Genotypic mutation analysis in the p53 gene of benzo[a]pyrene-treated European flounder (Platichthys flesus).
Mutation research - 22 Jun 2000
Sueiro R A, Jenkins G J, Lyons B P, Harvey J S, Parry J M
Abstract excerpt
We have applied a genotypic mutation detection system (the Restriction Site Mutation (RSM) assay) to detect mutations in the marine teleost flounder (Platichthys flesus). The aim of this study was to evaluate this species as an environmental indicator of genotoxic exposure. We have used the model genotoxin benzo[a]pyrene (B[a]P) to determine the limits of mutation detection in the p53 gene of flounder liver DNA....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.