Article
BRCA1 gene mutations in women with papillary serous carcinoma of the peritoneum.
Obstetrics and gynecology - 1 Oct 1998
Bandera C A, Muto M G, Schorge J O, Berkowitz R S, Rubin S C, Mok S C
Abstract excerpt
OBJECTIVE: To compare BRCA1 mutations in papillary serous carcinoma of the peritoneum and papillary serous ovarian carcinoma. METHODS: Germline DNA from 17 consecutive patients with peritoneal carcinoma was screened for mutations in the BRCA1 gene using single-strand conformation polymorphism analysis. Shifted DNA bands were sequenced. Patients with germline BRCA1 mutations were screened for allelic loss in tumor...
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