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Article

Transcriptional regulation of human cardiac homeobox gene CSX1.

Biochemical and biophysical research communications - 16 Jun 2000

Shiojima I, Oka T, Hiroi Y, Nagai R, Yazaki Y, Komuro I

Abstract excerpt

Cardiac homeobox gene Csx/Nkx-2.5 is essential for normal heart development and morphogenesis and is the earliest marker for cardiogenesis. To elucidate the regulatory mechanisms of Csx/Nkx-2.5 expression, we have isolated and characterized the upstream regulatory region of human Csx/Nkx-2.5 (CSX1). Transfection of the reporter gene containing a 965-bp CSX1 5' flanking region indicated that this region confers...

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Identifiers

PMID: 10860827
DOI: 10.1006/bbrc.2000.2861

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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