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Article

Relation between food habits and p53 mutational spectrum in gastric cancer patients.

International journal of oncology - 1 Jul 2000

Fedriga R, Calistri D, Nanni O, Cortesi L, Saragoni L, Amadori D

Abstract excerpt

p53 tumour suppressor gene mutations were analysed in gastric cancer in relation to food habits and social class in 56 patients from a high risk region of Italy. Exons 5-8 were analysed with DGGE method on amplified DNA from formalin-fixed paraffin-embedded samples. All p53 mutations were observed in patients belonging to low social class and the majority of mutations were found in intestinal type cancers. A...

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Identifiers

PMID: 10853029
DOI: 10.3892/ijo.17.1.127

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