Article
N-acetyltransferase 1 and 2 polymorphisms in para-substituted arylamine-induced contact allergy.
The British journal of dermatology - 1 Jun 2000
Westphal G A, Reich K, Schulz T G, Neumann C, Hallier E, Schnuch A
Abstract excerpt
Sensitization to arylamines such as p-phenylenediamine is frequently diagnosed in patients with allergic contact dermatitis. Reactive metabolites of p-phenylenediamine might be produced in the skin by O-acetylation of N-hydroxylamines catalysed by local N-acetyltransferases (NATs). In this study,...
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