Article
Human arylamine N-acetyltransferase 2 polymorphism and susceptibility to allergic contact dermatitis.
International journal of dermatology - 1 Mar 2006
Nacak Muradiye, Erbagci Zulal, Aynacioglu A Sukru
Abstract excerpt
BACKGROUND: N-acetyltransferase 2 (NAT2) polymorphism may be involved in the pathogenesis of allergic contact dermatitis. OBJECTIVE: The present study was designed to evaluate whether acetylation polymorphism plays a role in the susceptibility to p-Phenylenediamine (PPD) sensitization. METHODS: The frequencies of seven NAT2 point mutations, namely G191A, C282T, T341C, C481T, G590A, A803G, and G857A, and genotypes...
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