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Article

Peroxisome proliferator-activated receptor gamma-dependent repression of the inducible nitric oxide synthase gene.

Molecular and cellular biology - 1 Jul 2000

Li M, Pascual G, Glass C K

Abstract excerpt

The peroxisome proliferator-activated receptor gamma (PPARgamma) is a member of the nuclear receptor superfamily that activates target gene transcription in a ligand-dependent manner. In addition, liganded PPARgamma can inhibit transcription of genes induced by gamma interferon (IFN-gamma) and/or lipopolysaccharides (LPSs), including the inducible nitric oxide synthase (iNOS) gene. Inhibition of the iNOS promoter...

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Source

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Identifiers

PMID: 10848596
DOI: 10.1128/MCB.20.13.4699-4707.2000
PMCID: PMC85890

Genes

SRC
STAT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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