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Article

A PPARgamma mutant serves as a dominant negative inhibitor of PPAR signaling and is localized in the nucleus.

Molecular and cellular endocrinology - 25 Apr 2000

Berger J, Patel H V, Woods J, Hayes N S, Parent S A, Clemas J, Leibowitz M D, Elbrecht A, Rachubinski R A, Capone J P, Moller D E

Abstract excerpt

The peroxisomal proliferator-activated receptors (PPARs) are members of the nuclear receptor superfamily that act as ligand-activated transcription factors. PPARgamma plays a critical role in regulating adipocyte differentiation and lipid metabolism. Recently, thiazolidinedione (TZD) and select n...

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Identifiers

PMID: 10854698
DOI: 10.1016/s0303-7207(00)00211-2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-10854698-2026-09-04.1. Manifest publication-graph-cohort-2026-09-04.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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