Apolipoprotein E gene polymorphisms and serum cholesterol in healthy Irish adults: a proposed genetic marker for coronary artery disease risk.

doi:10.1007/BF03170486

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Article

Apolipoprotein E gene polymorphisms and serum cholesterol in healthy Irish adults: a proposed genetic marker for coronary artery disease risk.

Irish journal of medical science - 1 Jan 2000

Sheehan D, Bennett T, Cashman K

Abstract excerpt

BACKGROUND: The apolipoprotein (Apo) E gene, and thus its gene product, plays a central and pervasive role in lipid metabolism by serving as a ligand for lipoprotein receptors. Polymorphisms of this gene have been associated with variation in lipid phenotypes in some Caucasian and Asian populations, but not in others. No such study has been carried out in a resident Irish population. AIM: A study was designed to...

Topics

Adult
Aged
Apolipoprotein E2
Apolipoprotein E3
Apolipoprotein E4
Apolipoproteins E
Cholesterol, HDL
Cholesterol, LDL
Coronary Disease
Female
Genetic Markers
Genotype
Humans
Ireland
Male
Middle Aged
Polymorphism, Restriction Fragment Length
Risk Factors

Source

Open in PubMed

Identifiers

PMID: 10846860
DOI: 10.1007/BF03170486

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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