Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Novel type I restriction specificities through domain shuffling of HsdS subunits in Lactococcus lactis.

Molecular microbiology - 1 May 2000

O'Sullivan D, Twomey D P, Coffey A, Hill C, Fitzgerald G F, Ross R P

Abstract excerpt

This study identifies a natural system in Lactococcus lactis, in which a restriction modification specificity subunit resident on a 6159 bp plasmid (pAH33) alters the specificity of a functional R/M mechanism encoded by a 20.3 kb plasmid, pAH82. The new specificity was identified after phenotypic and molecular analysis of a 26.5 kb co-integrate plasmid (pAH90), which was detected after bacteriophage challenge of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Sequence
Share to Bacterial Proteins

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to DNA, Bacterial

Share to DNA Restriction-Modification Enzymes

Share to Lactococcus lactis

Share to Plasmids

Share to Recombination, Genetic

Share to Sequence Homology, Amino Acid

Source

Identifiers

PMID: 10844674
DOI: 10.1046/j.1365-2958.2000.01901.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Novel type I restriction specificities through domain shuffling of HsdS subunits in Lactococcus lactis.PMID 10844674Read ↗

Genetic analysis of regions of the Lactococcus lactis subsp. lactis plasmid pRS01 involved in conjugative transfer.Semantic proximity Read ↗

Improved transformation efficiency of group A Streptococcus by inactivation of a type I restriction modification system.Semantic proximity Read ↗

Identification of a Novel Hybrid Plasmid Encoding KPC-2 and Virulence Factors in Klebsiella pneumoniae Sequence Type 11Semantic proximity Read ↗

Improved transformation efficiency of group A <i>Streptococcus</i> by inactivation of a type I restriction modification systemSemantic proximity Read ↗

Distinctive features of homologous recombination in an 'old' microorganism, Lactococcus lactis.Semantic proximity Read ↗

Characterization of AbiR, a novel multicomponent abortive infection mechanism encoded by plasmid pKR223 of Lactococcus lactis subsp. lactis KR2.Semantic proximity Read ↗

Lactococcus lactis DPC5598, a plasmid-free derivative of a commercial starter, provides a valuable alternative host for culture improvement studies.Semantic proximity Read ↗

S treptococcus pneumoniae R 6 interspecies transformation: genetic analysis of penicillin resistance determinants and genome‐wide recombination eventsSemantic proximity Read ↗

Sau42I, a BcgI-like restriction-modification system encoded by the Staphylococcus aureus quadruple-converting phage Phi42.Semantic proximity Read ↗

Adaptation to the environment: Streptococcus pneumoniae, a paradigm for recombination-mediated genetic plasticity?Semantic proximity Read ↗

Regulation of natural genetic transformation and acquisition of transforming DNA in Streptococcus pneumoniaeSemantic proximity Read ↗

Interspecies recombination, not de novo mutation, maintains virulence after β-lactam resistance acquisition in Streptococcus pneumoniae.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.