Case-Control Association Studies for the Genetics of Complex Respiratory Diseases

Abstract excerpt

In this issue of the Red Journal, Maliarik and colleagues present a case-control association study that examines the relationship between several polymorphic markers within the natural resistance‐associated macrophage protein (NRAMP1) gene and sarcoidosis. Sarcoidosis is a chronic granulomatous disorder of unknown cause, which is likely a “complex” disease (1). The principal distinction between simple monogenic...

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