Article
Evaluation of lymph node virus burden in human immunodeficiency virus-infected patients receiving efavirenz-based protease inhibitor--sparing highly active antiretroviral therapy.
The Journal of infectious diseases - 1 Apr 2000
Dybul M, Chun T W, Ward D J, Hertogs K, Larder B, Fox C H, Orenstein J M, Baird B F, Li Y, Green L G, Engel D, Liu S, Mican J M, Fauci A S
Abstract excerpt
Although efavirenz-containing regimens effectively suppress plasma levels of human immunodeficiency virus (HIV) RNA, it is now clear that undetectable plasma viremia may not reflect a lack of viral replication. Because lymphoid tissue is an active site of HIV replication, the lymph node virus burden was analyzed in persons who received highly active antiretroviral therapy (HAART) containing either efavirenz or a...
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