Article
Rapid up-regulation of the neuronal serotoninergic phenotype by brain-derived neurotrophic factor and cyclic adenosine monophosphate: relations with raphe astrocytes.
Journal of neuroscience research - 15 Aug 2005
Rumajogee Prakasham, Vergé Daniel, Darmon Michèle, Brisorgueil Marie-Jeanne, Hamon Michel, Miquel Marie-Christine
Abstract excerpt
Up-regulation of the neuronal serotoninergic phenotype in relation to astrocytic population was studied in primary cultures of rat embryonic rostral raphe. Short treatments (18 hr at day in vitro 4) with brain-derived neurotrophic factor (BDNF) or dibutyryl-cAMP (dBcAMP) increased the number of serotoninergic neurons by approximately 80% and approximately 40%, respectively, and markedly enhanced the branching (by...
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