Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Differential expression of antiapoptotic genes in human endometrial carcinoma: bcl-XL succeeds bcl-2 function in neoplastic cells.

Gynecologic oncology - 1 Jun 2000

Crescenzi E, Criniti V, Pianese M, Tecce M F, Palumbo G

Abstract excerpt

OBJECTIVES: Previous histochemical observations have suggested a possible involvement of the bcl-2 family genes in the acquisition of neoplastic phenotype of the endometrium. Since knowledge of the type and function of genes controlling the transformed cell may result in new diagnostic, prognostic, and therapeutic approaches, we have investigated at the molecular level the biological role of bcl-2 family genes in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Apoptosis
Share to bcl-X Protein
Share to Carcinoma, Adenosquamous

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cell Transformation, Neoplastic

Share to Endometrial Neoplasms

Share to Genes, bcl-2

Share to Proto-Oncogene Proteins c-bcl-2

Share to Tumor Cells, Cultured

Source

Identifiers

PMID: 10831353
DOI: 10.1006/gyno.2000.5803

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Differential expression of antiapoptotic genes in human endometrial carcinoma: bcl-XL succeeds bcl-2 function in neoplastic cells.PMID 10831353Read ↗

Differential Expression of Members of the bcl-2 Gene Family in Proliferative and Secretory Human Endometrium: Glandular Epithelial Cell Apoptosis Is Associated with Increased Expression of baxSemantic proximity Read ↗

Bcl-2 overexpression results in reciprocal downregulation of Bcl-XL and sensitizes human testicular germ cell tumours to chemotherapy-induced apoptosisSemantic proximity Read ↗

Bcl-xL mediates therapeutic resistance of a mesenchymal breast cancer cell subpopulationSemantic proximity Read ↗

Expression of the <i>bcl</i>‐2 gene family in normal and malignant breast tissue: Low <i>bax</i>‐α expression in tumor cells correlates with resistance towards apoptosisSemantic proximity Read ↗

Anti-apoptotic Bcl-2 proteins: structure, function and relevance for radiation biologySemantic proximity Read ↗

BCL-XL directly modulates RAS signalling to favour cancer cell stemness.Semantic proximity Read ↗

Synthesis of Bcl-2 in response to anthracycline treatment may contribute to an apoptosis-resistant phenotype in leukemic cell lines.Semantic proximity Read ↗

Distinct Roles of Bcl-2 and Bcl-Xl in the Apoptosis of Human Bone Marrow Mesenchymal Stem Cells during DifferentiationSemantic proximity Read ↗

Expression of apoptosis-related proteins in Barrett's metaplasia-dysplasia-carcinoma sequence: a switch to a more resistant phenotype.Semantic proximity Read ↗

Expression of members of the bcl-2 gene family in the immature rat ovary: equine chorionic gonadotropin-mediated inhibition of granulosa cell apoptosis is associated with decreased bax and constitutive bcl-2 and bcl-xlong messenger ribonucleic acid levels.Semantic proximity Read ↗

Significant augmentation of pro-apoptotic gene therapy by pharmacologic bcl-xl down-regulation in mesothelioma.Semantic proximity Read ↗

Apoptosis and Chemoresistance in Human Ovarian Cancer: Is Xiap a Determinant?Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.