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Article

Cytoskeletal organization defects and abortive activation in human oocytes after IVF and ICSI failure

1 Jun 2000

Abstract excerpt

In this study, we analysed the distribution of beta tubulins to detect spindle and cytoplasmic microtubules, alpha acetylated tubulins for sperm microtubules and chromatin configuration in oocytes showing fertilization failure after conventional IVF or intracytoplasmic sperm injection (ICSI). A total of 450 human oocytes that failed to fertilize were studied 20-40 h after IVF or ICSI. In all, 287 oocytes were...

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PMID: 10825367
DOI: 10.1093/molehr/6.6.510

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