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Configuration of maternal and paternal chromatin and pertaining microtubules in human oocytes failing to fertilize after intracytoplasmic sperm injection

1 Feb 2000

Abstract excerpt

The microtubules and chromosomes of 180 human oocytes failing to fertilize after intracytoplasmic sperm injection were observed in order to establish how sperm chromatin and sperm astral microtubule configuration is related to the phases of oocyte cell cycle, and to find the defects in those structures causing fertilization arrest. As many as 125 (69%) oocytes were arrested at metaphase II. In one-fourth of them,...

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PMID: 10618659
DOI: 10.1002/(sici)1098-2795(200002)55:2<197::aid-mrd9>3.0.co;2-q

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