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Article

Adrenocortical carcinoma is characterized by a high frequency of chromosomal gains and high-level amplifications

1 Jun 2000

Abstract excerpt

Distinction of adrenocortical carcinoma from benign adrenocortical lesions by standard criteria is often difficult. In order to search for additional diagnostic parameters, a series of 25 adrenocortical tumors, 8 adenomas, 14 primary carcinomas, 1 metastasis, and the 2 adrenocortical carcinoma cell lines SW13 and NCI-H295 were analyzed by the approach of comparative genomic hybridization (CGH). Except for the two...

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PMID: 10824999
DOI: 10.1002/(sici)1098-2264(200006)28:2<145::aid-gcc3>3.0.co;2-7

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