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Structure and chromosomal localization of human and mouse genes for hematopoietic prostaglandin D synthase

1 Jun 2000

Abstract excerpt

Hematopoietic prostaglandin D synthase (H-PGDS) is the key enzyme for the production of the D and J series of prostanoids, and the first recognized vertebrate homolog of sigma-class glutathione S-transferase (GST). We isolated the genes and cDNAs for human and mouse H-PGDSs. The human and mouse cDNAs contained a coding region corresponding to 199 amino-acid residues with calculated molecular masses of 23 343 and...

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PMID: 10824118
DOI: 10.1046/j.1432-1327.2000.01362.x

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