Article
Primary Structure of Mouse and Rat Nephrin cDNA and Structure and Expression of the Mouse Gene
1 Jun 2000
Abstract excerpt
Nephrin is a central component of the glomerular podocyte slit diaphragm and is essential for the normal renal filtration process. This study describes the complete structure of the mouse nephrin gene, which was shown to be homologous to the human gene, the major difference being 30 exons in the mouse gene as opposed to 29 in human. The complete primary structure of mouse and rat nephrins was also determined. The...
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