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Article

Molecular defects causing ovarian dysfunction.

Annals of the New York Academy of Sciences - 1 Jan 2000

Kalantaridou S N, Chrousos G P

Abstract excerpt

The functions of the hypothalamic-pituitary-ovarian and -adrenal axes are intertwined, and molecular defects in either axis may cause ovarian dysfunction. Advances in molecular genetics have allowed new insights into the pathophysiology of ovarian disorders. Specific gene mutations causing delayed puberty and/or ovarian failure, and heterosexual or isosexual precocious puberty have recently been described. The...

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PMID: 10818390
DOI: 10.1111/j.1749-6632.2000.tb06214.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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