Article
The genetics of ovarian cancer: molecular biology and clinical application.
Obstetrical & gynecological survey - 1 Apr 1998
DePasquale S E, Giordano A, Donnenfeld A E
Abstract excerpt
Ovarian cancer is the fifth most common malignancy among American women and the fourth leading cause of cancer death. The rapid advances in molecular genetic analysis, presymptomatic detection, and treatment of ovarian cancer are staggering. In this review, both the genetic component and the mole...
Topics
- Breast Neoplasms
- Colorectal Neoplasms, Hereditary Nonpolyposis
- Female
- Genes, BRCA1
- Genes, Tumor Suppressor
- Genetic Counseling
- Humans
- Mutation
- Ovarian Neoplasms
- Proto-Oncogenes