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Article

SspA is required for lethal Salmonella enterica serovar Typhimurium infections in calves but is not essential for diarrhea.

Infection and immunity - 1 Jun 2000

Tsolis R M, Adams L G, Hantman M J, Scherer C A, Kimbrough T, Kingsley R A, Ficht T A, Miller S I, Bäumler A J

Abstract excerpt

Salmonella pathogenicity island 1 (SPI-1) encodes virulence determinants, which are important for enteropathogenicity in calves. To determine whether the Salmonella enterica serovar Typhimurium SPI-1 effector proteins SspA and SptP are important for enteropathogenicity, strains lacking these proteins were tested during oral infection of calves. Calves infected with a sptP mutant or its isogenic parent developed...

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Identifiers

PMID: 10816458
DOI: 10.1128/IAI.68.6.3158-3163.2000
PMCID: PMC97552

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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