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Article

Prevalence of drug resistant mutants and virological response to combination therapy in patients with primary HIV-1 infection.

Journal of medical virology - 1 Jun 2000

Tamalet C, Pasquier C, Yahi N, Colson P, Poizot-Martin I, Lepeu G, Gallais H, Massip P, Puel J, Izopet J

Abstract excerpt

Baseline genotype resistance analysis was carried out in 48 adults with primary HIV-1 infection between 1995 and 1998 before starting early combination therapy. Seventeen percent (8/48) of the isolates displayed key mutations conferring resistance to reverse transcriptase (RT) inhibitors such as amino acid substitutions 215Y/F (5/48,10%), 70R (3/48, 6%), 184V (2%). Two percent (1/48) had a major mutation...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 10797372
DOI: 10.1002/(sici)1096-9071(200006)61:2<181::aid-jmv2>3.0.co;2-t

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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