Article
Phenotypic and genotypic characterization of commonly used human prostatic cell lines.
BJU international - 1 May 2000
Mitchell S, Abel P, Ware M, Stamp G, Lalani E
Abstract excerpt
OBJECTIVE: To investigate and catalogue systematically the phenotypic and genotypic characteristics of the commonly used prostatic cell lines using immunocytochemistry and polymerase chain reaction (PCR) of hypervariable sequences within the genome to provide a 'fingerprint' characteristic of each cell line. Materials and methods Malignant (LNCaP, LNCaP-r, PC-3, DU-145) and benign immortalized prostatic cell...
Topics
- Cadherins
- DNA Fingerprinting
- Genome, Human
- Genotype
- Humans
- Immunohistochemistry
- Male
- Phenotype
- Polymerase Chain Reaction
- Prostatic Neoplasms
- Tumor Cells, Cultured
