Article
The importance of genetic polymorphisms in renal transplantation.
Current opinion in urology - 1 Mar 2000
Suthanthiran M
Abstract excerpt
Genetic variations including single nucleotide polymorphisms, dinucleotide repeats and microsatellites have been identified in a number of genes encoding cytokines, cytokine receptors, chemokines and their receptors, adhesion molecules. Several of the polymorphisms are located in the promoter region of the gene, affect transcription or translation, and not infrequently determine the level of expression of the...
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