Article
The human papillomavirus type 16 negative regulatory RNA element interacts with three proteins that act at different posttranscriptional levels
18 Apr 2000
Abstract excerpt
In human papillomaviruses, expression of the late genes L1 and L2, encoding the capsid proteins, is restricted to the upper layers of the infected epithelium. A 79-nt GU-rich negative regulatory element (NRE) located at the 3' untranslated region of the human papillomavirus 16 L1 gene was identified previously as key to the posttranscriptional control of late gene expression. Here, we demonstrate that in...
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