Article
Ras signaling is involved in the expression of Fas-L in glioma.
Laboratory investigation; a journal of technical methods and pathology - 1 Apr 2000
Yang B C, Wang Y S, Liu H S, Lin S J
Abstract excerpt
Fas-L expresses on a variety of tumors and is suspected to modify the dialog between tumor and the immune system. However, the cellular abnormality in tumor cells leading to an aberrant expression of Fas-L is unclear. In this study, we demonstrate the involvement of Ras signaling in the Fas-L expression in several ways. First, the activated Ha-rasval12 gene enhanced the Fas-L expression of primary human glial...
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