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RAS signaling and immune cells: a sinister crosstalk in the tumor microenvironment

5 Sept 2023

Abstract excerpt

The rat sarcoma virus (RAS) gene is the most commonly mutated oncogene in cancer, with about 19% of cancer patients carrying RAS mutations. Studies on the interaction between RAS mutation and tumor immune microenvironment (TIM) have been flourishing in recent years. More and more evidence has proved that RAS signals regulate immune cells' recruitment, activation, and differentiation while assisting tumor cells to...

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PMID: 37670322
DOI: 10.1186/s12967-023-04486-9

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