Article
Linkage and association studies of the lipoprotein lipase gene with postheparin plasma lipase activities, body fat, and plasma lipid and lipoprotein concentrations: the HERITAGE Family Study.
Metabolism: clinical and experimental - 1 Apr 2000
Garenc C, Pérusse L, Gagnon J, Chagnon Y C, Bergeron J, Després J P, Province M A, Leon A S, Skinner J S, Wilmore J H, Rao D C, Bouchard C
Abstract excerpt
Lipoprotein lipase (LPL) is responsible for the hydrolysis of triglyceride (TG)-rich lipoproteins. The aims of the present study were (1) to test for potential linkages (sib-pair method) between postheparin plasma lipase (lipoprotein and hepatic lipase) activities, body fatness, plasma lipid concentrations, and LPL polymorphisms (Ser447Ter and a tetranucleotide repeat) and microsatellite markers flanking the LPL...
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