Article
Lipoprotein lipase activity is decreased in a large cohort of patients with coronary artery disease and is associated with changes in lipids and lipoproteins.
Journal of lipid research - 1 Apr 1999
Henderson H E, Kastelein J J, Zwinderman A H, Gagné E, Jukema J W, Reymer P W, Groenemeyer B E, Lie K I, Bruschke A V, Hayden M R, Jansen H
Abstract excerpt
Lipoprotein lipase (LPL) is crucial in the hydrolysis of triglycerides (TG) in TG-rich lipoproteins in the formation of HDL particles. As both these lipoproteins play an important role in the pathogenesis of atherosclerotic vascular disease, we sought to assess the relationship between post-heparin LPL (PH-LPL) activity and lipids and lipoproteins in a large, well-defined cohort of Dutch males with coronary...
Topics
- Adult
- Apolipoproteins E
- Cholesterol
- Cohort Studies
- Coronary Disease
- Double-Blind Method
- Fasting
- Humans
- Lipids
- Lipoprotein Lipase
- Lipoproteins