Article
A Monoclonal Antibody to Human SP-10 Inhibits In Vitro the Binding of Human Sperm to Hamster Oolemma but Not to Human Zona Pellucida
1 May 2000
Abstract excerpt
SP-10 is a sperm intra-acrosomal protein, specific to the testis, that is believed to play an important role in egg-sperm binding. While the molecular characterization of the SP-10 protein has been clarified, little is yet known of its functional role in fertilization. We therefore established a monoclonal antibody (mAb pep-SP10) against a peptide (pep-SP10) that included the most hydrophilic portion of human...
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