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Article

FLB1, a Human Protein of Epididymal Origin that is Involved in the Sperm-Oocyte Recognition Process

1 Feb 1995

Abstract excerpt

CA6 antibody was selected out of a monoclonal antibody library raised against human sperm proteins primarily for its ability to recognize an epididymal antigen and to modify sperm adhesion to zona-free hamster oocytes. In the present study, CA6 was shown to decrease sperm binding to zona-free hamster and human oocytes by 40-92% and 38-48%, respectively. The corresponding protein, which was referred to as FLB1,...

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PMID: 7536047
DOI: 10.1095/biolreprod52.2.267

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