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Article

A novel HLA-B39 allele (HLA-B3916) due to a rare mutation causing cryptic splice site activation.

Human immunology - 1 May 2000

Tamouza R, El Kassar N, Schaeffer V, Carbonnelle E, Tatari Z, Marzais F, Fortier C, Poirier J C, Sadki K, Bernaudin F, Toubert A, Krishnamoorthy R, Charron D

Abstract excerpt

A novel HLA-B*39 variant, found in an African patient with sickle cell anemia undergoing bone marrow transplantation is described. Initially suspected by inconsistent serological typing (B-blank, Bw6), then recognized by PCR-SSP, and finally characterized by nucleotide sequencing, this novel allele is designated HLA-B*3916. It differs from HLA-B*3910 by a point mutation (G to C) at position 17 of exon 3 causing...

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PMID: 10773349
DOI: 10.1016/s0198-8859(00)00108-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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