Theoretical study of near neutrality. I. Heterozygosity and rate of mutant substitution.

doi:10.1093/genetics/126.1.219

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Article

Theoretical study of near neutrality. I. Heterozygosity and rate of mutant substitution.

Genetics - 1 Sept 1990

Ohta T, Tachida H

Abstract excerpt

In order to clarify the nature of "near neutrality" in molecular evolution and polymorphism, extensive simulation studies were performed. Selection coefficients of new mutations are assumed to be small so that both random genetic drift and selection contribute to determining the behavior of mutan...

Topics

Biological Evolution
Gene Frequency
Heterozygote
Models, Genetic
Monte Carlo Method
Mutation
Polymorphism, Genetic
Selection, Genetic

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