Article
Factor V leiden increases plasma F1+2 levels both in normal and deep venous thrombosis subjects.
Haematologica - 1 Apr 2000
Mercuri F, Giacomello R, Puglisi F, Colaone R, Fabbro D, Menegon M G, Ceriello A, Gonano F, Damante G
Abstract excerpt
BACKGROUND AND OBJECTIVE: A simple approach to understanding molecular mechanisms leading to thrombosis is the definition of how genetic factors influence biochemical parameters of coagulation. Conflicting data have been reported regarding the role that the genotype of factor V plays in the control of plasma F1+2 levels. The aim of this study was to test whether the factor V Leiden mutation affects F1+2 levels....
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