The incidence of the factor V Leiden mutation in an obstetric population and its relationship to deep vein thrombosis.

doi:10.1016/s0002-9378(97)70615-x

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Article

The incidence of the factor V Leiden mutation in an obstetric population and its relationship to deep vein thrombosis.

American journal of obstetrics and gynecology - 1 Apr 1997

Dizon-Townson D S, Nelson L M, Jang H, Varner M W, Ward K

Abstract excerpt

OBJECTIVE: A common missense mutation in the factor V gene, the Leiden mutation, renders factor Va resistant to cleavage inactivation by activated protein C and predisposes patients to thrombotic events. We sought to evaluate the prevalence of the Leiden mutation and the associated thromboembolic...

Topics

Adult
Disseminated Intravascular Coagulation
Factor V
Female
Humans
Incidence
Mutation
Pregnancy
Pregnancy Complications, Cardiovascular
Puerperal Disorders
Thrombophlebitis

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